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Exogenous glutathione exerts a therapeutic effect in ischemic stroke rats by interacting with intrastriatal dopamine

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Research demonstrates that BNIP3/NIX-mediated mitophagy orchestrates mitochondrial dynamics homeostasis through dual regulatory mechanisms: by suppressing the activity of fusion protein Opa1 while enhancing fission protein Drp1 functionality to induce mitochondrial network fragmentation, thereby facilitating segregation of damaged organelles